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Psilocybin trip report in Scientific American

SciAm publishes a full-on trip report from one of the participants in Roland Griffith's study on psilocybin and spirituality.

Mary and Matt, my guides, sat beside me on the couch at Johns Hopkins Medical Center to look at an art book until the psilocybin took effect. In only about fifteen or twenty minutes I knew I had received an active dose rather than a placebo. "I'm going down," I told them. On went the eye mask, the headphones, the blanket, and the blood pressure cuff, and I began to sink into another world.

The descent seemed even rougher than the previous time, a rattling, lurching, high-speed roller coaster ride straight downhill through tingling geometric shapes and tunnels of textured blackness. The music on the soundtrack exaggerated the eerie atmosphere and kept me wary. Once again the abdominal spasms started up as well. Chemicals washed over me in repeated waves, bringing hot sensations and a bad taste in my mouth. As soon as I managed to get stabilized from one wave, another would follow. The sheer number of these cycles suggested that this was a stronger dose than I'd had the first time...

I also came upon another impression that I had forgotten from the first session, the sense of emerging into "rooms" or public areas in the blackness. Sometimes I seemed to be on the periphery of a large sphere, many stories tall, with a city-of-the-future feel to it, tiers of terraces around the edge and flying objects like space cars. For all I knew, this could have been a single cell -- all sense of proportion was lost. I described this to Mary and Matt for their records.

Despite the strong effects of the psilocybin, I was able to keep in mind my intention to work with what was presented to me. Whenever my consciousness regrouped into my familiar identity, I mentally reiterated, "Tell me where we are going. I am willing to go where you take me." I was determined to remain as nonjudgmental as possible and to offer no resistance, as Dr. Griffiths had advised, even though I was apprehensive.

Before the session began that morning, I had asked various sources of spiritual inspiration, ranging from the Archangel Michael to Joel Goldsmith, author of The Infinite Way, to help me through the experience. Now when I silently called on them to come and be with me, I detected a sense of wry amusement as if they had been watching. "We are already here," they responded wordlessly. "It is you who are in our territory now." I told this to Mary and she too found it surprising. I felt the truth of their message, and it heartened me. This was my first encounter with other intelligence in an altered state.

Posted By jamesk at 2010-11-29 15:18:43 permalink | comments
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Mick. : 2014-02-05 06:25:09
Bradley, this is a trip report from one participant of a study organised as you suggest...
Bradley. : 2011-02-23 00:29:38
See: [link]

That is a critique noting lack of control group, blinding, and use of vague terms.

My comment to SCIAM shortly after reading the article:

I note that the report appears to be anecdotal accounts centered on culturally acquired beliefs and expectations of hand-picked participants without a control group for comparison. For a drug to be shown to be of benefit for psychiatric use a protocol including items similar to the following is widely thought to be necessary in order to minimize bias:

1. Standardized selection of participants, i.e., the participants must all be selected according to the same checklist of criteria in which particular behavioral and/or emotional issues are indentified.

2. A statistically significant number of participants must be used, particularly to minimize bias due to drop-outs as well as to be representative of the population at large.

3. Participants must be randomly assigned to either the drug group or a placebo group while both groups receive the same scripted therapy, e.g., talk therapy, guided insight therapy, etc.

4. A control group given no drug at all but undergoing a different standardized therapy must be included for comparison.

5. Follow-up evaluations per original criteria should be conducted at timely intervals, e.g., 6 months, 1 year, 2 years.

I did not see any of this mentioned in the article, but rather what appears to be selection of participants and analysis of outcome by a more or less personalized schema. Given that there are no alternate settings sans psilocybin to compare, the analysis is useless for science, it does not tell us anything other than researchers will tend to see only what they want to see when they set up a scenario to reveal only what they want to see.

It is not surprising to me that SCIAM’s editorial take on this article is less than rigorous. I would hope that the same lack of rigor is not true of the authors. Currently the most widespread problem in psychiatry is that it has long ago become a subsidiary of the pharmaceutical industry. SCIAM in general is beholden to industry sources [not necessarily the case here], and indeed so are many psychiatrists and other doctors who readily dispense so-called psychiatric medications like so many magic pills, even if the medications work no better than placebos, and even if the medications might cause brain damage (e.g., tardive dyskinesia resulting from use of neuroleptics).

guest : 2010-11-30 08:54:28
the trip report was INTENSE lol

How much did he do?

motley. : 2010-11-30 05:28:18
some of the comments show well complete ignorance and a lack of the scientific enquiry maybe.
Lissamphibia. : 2010-11-30 00:18:01
The comments from the Scientific American readership are very interesting... personally, I agree with the Teafaerie's stance on discarnate entities, from her amazing essay "To Believe or Not to Believe":
[link]

Mason. : 2010-11-29 19:34:39

Outstanding

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